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This is minimized if the blood is also diluted directly by pre-charging the syringe with a volume of saline containing EDTA (4 mM) at twice the required final concentration (Solution C)

B., Laczi, F., Tonnaer, J

Similarly, in bipolar disorder, particularly during depressive episodes, patients exhibit altered energy metabolism marked by increased lactate levels and decreased glucose and glycine levels, which parallels results in ME/CFS that suggest TCA impairment and energy metabolism dysregulation (Yamano et al., 2016

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